The Center for Muscle Biology Core Facilities are located on UK's campus in the Charles T. Wethington (CTW) Building and the Multidisciplinary Science (MDS) Building.
MIMIC
The Muscle Immunohistochemistry and Molecular Imaging Core (MIMIC) offers expertise, training and protocols for researchers working with muscle, including sectioning of frozen muscle tissue, histological and immunohistochemical muscle characterization and imaging of common muscle features. MIMIC provides access to automated image analyses software MyoVision Basic for download, and will provide high throughput image quantification upon request.
We are proud to support basic, clinical and translation research aimed at understanding the mechanisms underlying the regulation of muscle structure and function and the impact on physical activity and chronic disease.
Muscle Function Core
Located in CTW 429, the Muscle Function Core has the Aurora system to carry out whole ex-vivo muscle functional analyses. Functional properties that can be determined include specific force, calcium sensitivity, rate of tension recovery, passive and active muscle stiffness, and break length. For more information, please contact Dr. Tim Butterfield.
The Human Performance Lab, which also houses the Biodynamics and Biomotion labs, was established in 2013, and enables CMB researchers to translate their research findings to humans. Located in the Multidisciplinary Science Building, the lab contains equipment capable of assessing physical function, strength, fatigue, biomechanics, range of motion, and gait, as well as for exercise training; computers with all software necessary for data collection and analysis are also onsite. A list of all equipment can be found here. The lab interfaces closely with the CCTS Clinical Services Core, where muscle biopsies are performed for the Human Muscle Resources. For more information about the Human Performance Lab, please contact Doug Long.